Effect of bisphenol A on formation and process of alergic reaction - review

Sun, 31 Dec 2023 00:00:00 +0100

One of the possible immunomodulatory effects of BPA is alterating the allergy process and asthma. The growth in the prevalence of asthma around the world roughly corresponds with the rise in the widespread usage of certain chemicals. Despite the fact that asthma is a complicated and varied condition brought on by exposure to a variety of environmental factors and genetic predispositions, many classes of chemicals that are frequently present in the surrounding environment and are linked to endocrine disruption have recently been linked to the disease's pathogenesis. BPA is endocrine disrupting chemical compound made up of two phenol rings joined by a methyl bridge and two methyl functional groups adhered to the bridge. BPA is ingested by humans, inhaled via home dust, and exposed through the skin. An allergy is an aberrant immunological reaction to an antigen, such as a protein or allergen. An ingested or breathed allergen encounters the epithelium as its initial barrier. The inflammatory condition and increased permeability of the epithelial barrier are associated with allergic inflammatory disorders, and this suggests that the epithelium barrier is more sensitive to allergen sensitization. The existing literature and scientific publications do not adequately address the direct influence of bisphenols on the development and influence of the allergic process. Multiple authors discuss how bisphenol affects specific allergic response components. We may conclude that exposure to bisphenol A alters the allergic response based on the findings of the studies and the analysis of the literature.

Isolation and screening of crude oil-degrading microbes from contaminated sites in Koko Community, Delta State, Nigeria

Sun, 31 Dec 2023 00:00:00 +0100

The potential use of these isolated microbes for bioremediation of contaminated sites in Koko Community, Delta State, Nigeria. Bioremediation is an attractive option for reducing the environmental damage caused by crude oil contamination. This study aimed at isolating and screening a consortium of indigenous oil microbes with biodegradation capabilities from an oil-polluted spilled site situated in Koko community Delta State, South-Southern, Nigeria. The samples were collected from the farm soil and the river water in the area. The hydrocarbon utilizing bacteria (HUC), The heterotrophic place count (HPC), Total fungi count (TFC)and hydrocarbon-utilizing fungi (HFC were identified and enumerated using standard methods. The mean HPC, HUC and TFC and HFC for the crude polluted soil was (8.70 × 104 CFU/g, 8.20 × 104 CFU/g, 2.00 × 104 CFU/g and 1.90 × 104 CFU/g respectively), farm soil was (1.18 × 107 CFU/g, 5.90 × 104 CFU/g, 1.80 × 103 CFU/g and 1.80 × 103 CFU/g respectively), crude oil polluted river was (1.77 × 104 CFU/g, 1.15 × 104 CFU/g, 1.01 × 102 CFU/g and 6.60 × 101 CFU/g respectively) and for water was (4.50 × 103 CFU/g, 1.80 × 101 CFU/g, 3.00 × 101 CFU/g and 3.00 × 101 CFU/g respectively). The bacteria and fungi isolated were Bacillus sp., Citrobacter sp., Pseudomonas, Escherichia coli, Saccharomyces sp., Penicillium sp., Aspergillus sp. and Cladosporium sp. The results of this study may also be used to inform the management of crude oil-contaminated sites in similar environments as well as be employed to design and incorporate suitable strategies for effective monitoring and management of crude oil contamination in the environment. This study concludes that that the organisms isolated have biodegradable abilities and thus ideal candidates for bioremediation in oil spill polluted environment.

Archives of Ecotoxicology

Effect of bisphenol A on formation and process of alergic reaction - review

Isolation and screening of crude oil-degrading microbes from contaminated sites in Koko Community, Delta State, Nigeria